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Research paper
Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression

Authors

  • Andrew Geoffrey Bourne Thompson MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK NHS National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Connie Luk MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK PubMed articlesGoogle scholar articles
  • Amanda J Heslegrave Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK UK Dementia Research Institute at UCL, London, UK PubMed articlesGoogle scholar articles
  • Henrik Zetterberg Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK UK Dementia Research Institute at UCL, London, UK Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden PubMed articlesGoogle scholar articles
  • Simon H Mead MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK NHS National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • John Collinge MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK NHS National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK PubMed articlesGoogle scholar articles
  • Graham S Jackson MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Graham S Jackson, MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London WC1N 3BG, UK; g.jackson{at}prion.ucl.ac.uk
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Citation

Thompson AGB, Luk C, Heslegrave AJ, et al
Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression

Publication history

  • Received December 11, 2017
  • Revised January 25, 2018
  • Accepted February 11, 2018
  • First published February 27, 2018.

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