Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase

Patrick Oeckl; Patrick Weydt; Petra Steinacker; Sarah Anderl-Straub; Frida Nordin; Alexander E Volk; Janine Diehl-Schmid; Peter M Andersen; Johannes Kornhuber; Adrian Danek; Klaus Fassbender; Klaus Fliessbach; German Consortium for Frontotemporal Lobar Degeneration; Holger Jahn; Martin Lauer; Kathrin Müller; Antje Knehr; Johannes Prudlo; Anja Schneider; Dietmar R Thal; Deniz Yilmazer-Hanke; Jochen H Weishaupt; Albert C Ludolph; Markus Otto

doi:10.1136/jnnp-2018-318868

Article info

Neurodegeneration

Research paper

Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase

Authors

Patrick Oeckl Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Patrick Weydt Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Petra Steinacker Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Sarah Anderl-Straub Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Frida Nordin Department of Pharmacology and Clinical Neurosciences, Umeå University, Umeå, Sweden PubMed articles Google scholar articles
Alexander E Volk Institute of Human Genetics, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany PubMed articles Google scholar articles
Janine Diehl-Schmid Department of Psychiatry, Technical University of Munich, Munich, Germany PubMed articles Google scholar articles
Peter M Andersen Department of Neurology, Ulm University Hospital, Ulm, Germany Department of Pharmacology and Clinical Neurosciences, Umeå University, Umeå, Sweden PubMed articles Google scholar articles
Johannes Kornhuber Department of Psychiatry, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany PubMed articles Google scholar articles
Adrian Danek Department of Neurology, LMU Munich, Munich, Germany PubMed articles Google scholar articles
Klaus Fassbender Department of Neurology, Saarland University, Homburg, Germany PubMed articles Google scholar articles
Klaus Fliessbach Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn and DZNE Bonn, Bonn, Germany PubMed articles Google scholar articles
German Consortium for Frontotemporal Lobar Degeneration, University of Ulm, Ulm, Germany Google scholar articles
Holger Jahn Department of Psychiatry, University Hospital Hamburg, Hamburg, Germany PubMed articles Google scholar articles
Martin Lauer Department of Psychiatry and Psychotherapy, University of Würzburg, Würzburg, Germany PubMed articles Google scholar articles
Kathrin Müller Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Antje Knehr Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Johannes Prudlo Department of Neurology, University of Rostock, and German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany PubMed articles Google scholar articles
Anja Schneider Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn and DZNE Bonn, Bonn, Germany PubMed articles Google scholar articles
Dietmar R Thal Department of Neuroscience, KU Leuven and Department of Pathology, UZ Leuven, Belgium Laboratory of Neuropathology, Institute of Pathology, Ulm University, Ulm, Germany PubMed articles Google scholar articles
Deniz Yilmazer-Hanke Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Jochen H Weishaupt Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Albert C Ludolph Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles
Markus Otto Department of Neurology, Ulm University Hospital, Ulm, Germany PubMed articles Google scholar articles

Correspondence to Markus Otto, Department of Neurology, Ulm University Hospital, Ulm D-89081, Germany; markus.otto{at}uni-ulm.de

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Citation

Oeckl P, Weydt P, Steinacker P, et al

Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase

Journal of Neurology, Neurosurgery & Psychiatry 2019;90:4-10.

Publication history

Received May 22, 2018
Revised July 16, 2018
Accepted August 8, 2018
First published September 17, 2018.

Online issue publication

December 14, 2018

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