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Anatomical connectivity elucidated by analysing thalamic atrophy in neuromyelitis optica
  1. Masahiro Mori
  1. Department of Neurology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan
  1. Correspondence to Dr Masahiro Mori, Department of Neurology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan; morim{at}

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The thalamus serves various functions, but it primarily acts as a relay that receives sensory information and sends it to the cerebral cortex. In fact, inputs from the retina are sent to the lateral geniculate nucleus, which projects to the visual cortex in the occipital lobe. Meanwhile, the ventral posterior nucleus (VPN) is a key relay centre of somatosensory information that receives touch and proprioceptive information and sends it to the primary somatosensory cortex.

In research pertaining to multiple sclerosis (MS), the thalamus has been studied since long. Thalamic atrophy is often found in patients with clinically isolated syndrome and MS, …

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  • Contributors MM wrote the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

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