Can we TAG acute ischemic stroke patients with increased risk for symptomatic intracerebral haemorrhage following mechanical thrombectomy?

In the pivotal randomised clinical trials, patients with acute ischaemic stroke (AIS) with large-vessel occlusion (LVO) undergoing treatment with mechanical thrombectomy (MT), and preceding intravenous alteplase in 83% of the cases, had a total of 4.4% risk of postprocedural symptomatic intracerebral haemorrhages (sICH).1 Despite its relatively small incidence, sICH after MT has been highlighted as an independent predictor of long-term unfavourable functional outcomes and mortality, with a 10-fold increase in the risk of all-cause 3-month mortality with rates up to 72%.2

In the current issue of the Journal of Neurolog y, Neurosurgery and Psychiatry, Montalvo et al present the first stratification score on the risk of …