Article Text

Download PDFPDF
143 Dopamine transporter SPECT imaging: service evaluation from a tertiary neurosciences centre
  1. Christopher Kobylecki1,2,
  2. Jonathan Harris3,
  3. Mark Boyle3,
  4. Sandra Hoffmann3
  1. 1Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust
  2. 2University of Manchester
  3. 3Department of Nuclear Medicine, Salford Royal NHS Foundation Trust


Background The use of dopamine transporter SPECT imaging can improve diagnostic accuracy in the assessment of parkinsonism and tremors. In order to manage demand and ensure appropriate use, our tertiary neurosciences centre set up a policy of screening referrals by a movement disorder specialist (C.K.).

Objective To audit the use of [123I]-ioflupane SPECT (DaTscanTM) imaging at Manchester Centre for Clinical Neurosciences.

Methods We audited DaTscan referrals and subsequent results from May 2014-July 2018. The reason for rejection of referrals was documented and subsequent clinical course assessed. We recorded overall indications for imaging and the eventual results.

Results In total, we received 136 referrals for DaTscan, of which 34 (25%) were rejected. Of these, the subsequent course was consistent with the clinical impression in 30 patients for whom follow-up data were available. The most common indications for scans performed were differentiation of Parkinson’s disease from tremor syndromes (46%), and suspected drug induced parkinsonism (26%). Equivocal imaging results in 9% were reclassified as normal following quantification.

Conclusions Screening of referrals for DaTscan imaging in a movement disorder service is safe and cost-saving. Appropriate use of DaTscan imaging improves patient management, and equivocal results may be clarified by quantification techniques.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.