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Epilepsy surgery at its best: randomised prospective controlled trials in neurosurgery are no magic
  1. Peter C Warnke
  1. Neurosurgery, University of Chicago, Chicago, IL 60637, USA
  1. Correspondence to Professor Peter C Warnke, Neurosurgery, University of Chicago, Chicago, IL 60637, USA; pwarnke{at}

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A new way to look at epilepsy surgery outcomes

Three fields of neurosurgery have truly lived up to the aspirations of evidence-based medicine with multiple randomised controlled trials published in top impact journals: epilepsy surgery and movement disorder surgery and to a lesser degree stereotactic radiosurgery.1–3

The JNNP paper of Vogt et al 4adds another layer of granularity to the epilepsy surgery literature and shows quite clearly that randomised prospective trials in neurosurgery—so badly needed in many areas—are feasible and very useful.

Comparing two different approaches and hence techniques of performing selective amygdala-hippocampectomies (SAH) in a randomised prospective fashion is not an esoteric enterprise. First, the field naturally is moving towards more tailored minimally invasive surgical procedures in epilepsy surgery, relegating gross volumetric techniques like anterior temporal lobectomy hopefully to …

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  • Funding The author has not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

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