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P117 Predictive factors of outcome in poor grade subarachnoid haemorrhage (SAH)
  1. J Fahmy1,
  2. T Boumrah1,
  3. S Trippier2,
  4. A Hainsworth1,
  5. J Madigan3,
  6. E Pereira1,
  7. A Shtaya1,
  8. P Minhas4
  1. 1Molecular and Clinical Sciences Research Institute, St George’s University of London, London, UK
  2. 2Stroke Unit, St George’s University Hospital NHS Trust, London, UK
  3. 3Neuroradiology Department, St George’s University Hospital NHS Trust, London, UK
  4. 4Atkinson Morley Neurosurgery Centre, St George’s University Hospital NHS Trust, London, UK

Abstract

Objectives To study the factors associated with outcome in poor grade SAH in a busy tertiary centre.

Design Retrospective records review.

Subjects All Patients with SAH WFNS grades IV and V admitted Jan 2016-Dec 2017.

Methods We admitted 379 SAH patients, 84 (22%) were poor grade (n=84, 33M/51F mean age 60.7±1.4 y). Outcome was assessed by Modified Rankin Scale (mRS) scores before surgery and at latest follow up (3–6 months). mRS was dichotomised as good (0–3) and poor (4–6).Spearman’s rank-order test evaluated correlation between latest mRS and all other variables (WFNS grade, GCS, Motor score of GCS, age, sex, smoking, hypertension, intraventricular haemorrhage (IVH) and intracerebral haemorrhages (ICH)).

Results 63 patients (75%) had poor outcome, of which 46 (55%) died (44 with 30 days), versus 21 (25%) had good outcome. Spearman’s correlation analysis revealed that patients with smaller aneurysms (3.3±0.4 mm in good outcome patients vs 11.3±1.2 mm in poor outcome) (rs=0.37, p=0.009), who are younger (rs=0.24, p=0.03), have higher GCS (rs=−0.24, p=0.03), higher motor score (rs=0.25, p=0.02), lower WFNS grade (rs=0.3, p=0.007) and received coiling of aneurysms vs no treatment (rs=−0.39, p<0.0001) had better outcome. There was no significant correlation in outcome with ICH, IVH, external ventricular drain insertion, location of aneurysms, smoking, hypertension, other co-morbidities or sex.

Conclusions In poor grade SAH, younger patients with smaller aneurysms, higher GCS and higher motor score who received endovascular coiling had better outcome.

https://doi.org/10.1136/jnnp-2019-ABN.170

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