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ID and SR contributed equally.
Contributors ID, SR, KR and JBS contributed to conception and design of the study. ID, SR, CD, SM and KR contributed to the acquisition and analysis of the data. All authors contributed to drafting a significant portion of the manuscript and figure preparation, edited, and approved the final manuscript.
Funding All authors are part of the European Friedreich Ataxia Consortium for Translational Studies (EFACTS), which was funded in 2010–2015 by an FP7 Grant from the European Commission (HEALTH-F2-2010-242193). This project and the positions of KR and SR were funded by the German Federal Ministry of Education and Research (BMBF 01GQ1402 to KR); ID was supported by the START Program (08/16) of the Faculty of Medicine at the RWTH Aachen University; MS was supported by a grant from the Else Kröner-Fresenius Stiftung.
Competing interests None declared.
Patient consent Obtained.
Ethics approval Ethics Committee of the Medical Faculty of the RWTH Aachen University (EK 057/10).
Provenance and peer review Not commissioned; externally peer reviewed.
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