Article Text

Download PDFPDF
Corticolimbic fast-tracking in functional neurological disorders: towards understanding of the ‘dynamic lesion’ of Jean-Martin Charcot
  1. Selma Aybek
  1. Correspondence to Prof Dr med Selma Aybek, Department of Neurology, University Hospital Bern and University of Bern, Bern, 3010, Switzerland; selma.aybek{at}insel.ch

Statistics from Altmetric.com

Have we found the ‘dynamic lesion’ of Jean-Martin Charcot in functional neurological disorders?

At the end of the 19th century, hysterical symptoms were regarded by one of the founders of modern neurology, Jean-Martin Charcot, as manifestations of a ‘dynamic lesion’ of the central nervous system. In 1889, he wrote: ‘There is, without doubt, a lesion of the nervous centres but where is it situated and what is its nature? … But certainly, it is not of the nature of a circumscribed organic lesion of a destructive nature … one of those lesions which escape our present means of anatomical investigation, and which for want of a better term, we can designate dynamic or functional lesion’.1

After 130 years of tremendous developments in neurosciences, we are now in possession of powerful ‘means of anatomical investigation’ and the question is: has neuroimaging revealed this lesion? Its location and nature?

An …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles