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Plasma pNfH levels differentiate SBMA from ALS

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  • VL and AB contributed equally.

  • Contributors VL and AB contributed to the writing of the manuscript, statistical analysis, data acquisition and data analysis. LZ, BM, HZ, AJH, CR, LG and MGH contributed to the critical revision of the manuscript. AM and PF contributed to the design and conceptualisation of the study and the critical revision of the manuscript.

  • Funding Study Funded by the NIHR UCLH Biomedical Research Centre Grant #BRC279566.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval Ethical approval was obtained from the East London and the City Research Ethics Committee (09/H0703/27) and the Ethical Review Panel of UCL Institute of Neurology (PPL PE83401B1).

  • Provenance and peer review Not commissioned; externally peer reviewed.