Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration

Tamara Paulo Tavares; Derek G V Mitchell; Kristy KL Coleman; Brenda L Coleman; Christen L Shoesmith; Christopher R Butler; Isabel Santana; Adrian Danek; Alexander Gerhard; Alexandre de Mendonca; Barbara Borroni; Maria Carmela Tartaglia; Caroline Graff; Daniela Galimberti; Fabrizio Tagliavini; Fermin Moreno; Giovanni B Frisoni; James Benedict Rowe; Johannes Levin; John Cornelis Van Swieten; Markus Otto; Matthis Synofzik; Raquel Sanchez-Valle; Rik Vandenberghe; Robert Jr Laforce; Roberta Ghidoni; Sandro Sorbi; Simon Ducharme; Mario Masellis; Jonathan D Rohrer; Elizabeth Finger

doi:10.1136/jnnp-2020-322987

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This article has a correction. Please see:

Correction: Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration - December 01, 2020

Neurodegeneration

Original research

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration

Authors

Tamara Paulo Tavares Neuroscience, Brain and Mind Institute, University of Western Ontario, London, Ontario, Canada PubMed articles Google scholar articles
Derek G V Mitchell Psychiatry, Anatomy & Cell Biology, Brain and Mind Institute, University of Western Ontario, London, Ontario, Canada PubMed articles Google scholar articles
Kristy KL Coleman Cognitive Neurology, St. Joseph's Health Care, London, Ontario, Canada PubMed articles Google scholar articles
Brenda L Coleman Infectious Disease Epidemiologic Research Unit, Mount Sinai Hospital, Toronto, Ontario, CanadaDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada PubMed articles Google scholar articles
Christen L Shoesmith Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada PubMed articles Google scholar articles
Christopher R Butler Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Isabel Santana Neurology, Centro Hospitalar e Universitário de Coimbra, Coimbra, PortugalFaculty of Medicine, Centre of Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal PubMed articles Google scholar articles
Adrian Danek Neurologische Klinik und Poliklinik, Ludwig-Maximilians Universitat, Munich, Germany PubMed articles Google scholar articles
Alexander Gerhard Division of Neuroscience and Experimental Psychology, Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UKGeriatric Medicine and Nuclear Medicine, University of Duisburg-Essen, Duisburg, Germany PubMed articles Google scholar articles
Alexandre de Mendonca Laboratory of Neurosciences, Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, Lisbon, Portugal PubMed articles Google scholar articles
Barbara Borroni Centre for Neurodegenerative Disorders, Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy PubMed articles Google scholar articles
Maria Carmela Tartaglia Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, CanadaCanadian Sports Concussion Project, Toronto, Ontario, Canada PubMed articles Google scholar articles
Caroline Graff Geriatric Medicine, Karolinska University Hospital-Huddinge, Stockholm, Sweden PubMed articles Google scholar articles
Daniela Galimberti Neurodegenerative Diseases Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, ItalyCentro Dino Ferrari, University of Milan, Milano, Lombardia, Italy PubMed articles Google scholar articles
Fabrizio Tagliavini Neurology and Neuropathology, Fondazione Istituto Neurologico Carlo Besta, Milan, Italy PubMed articles Google scholar articles
Fermin Moreno Cognitive Disorders Unit, Department of Neurology, Donostia University Hospital Gipuzkoa Building, San Sebastian, País Vasco, SpainNeuroscience Area, Biodonostia Health Research Institute, Donostia-san Sebastian, Guipuzcoa, Spain PubMed articles Google scholar articles
Giovanni B Frisoni Instituto di Recovero e Cura a Carattere Scientifico Istituto Centro San Giovanni di Dio Fatebenefratell, Brescia, Italy PubMed articles Google scholar articles
James Benedict Rowe Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Johannes Levin German Center for Neurodegenerative Diseases (DZNE), Munich, GermanyDepartment of Neurology, University Hospital, LMU Munich, Munich, Germany PubMed articles Google scholar articles
John Cornelis Van Swieten Neurology, Erasmus MC, Rotterdam, The Netherlands PubMed articles Google scholar articles
Markus Otto Neurology, University of Ulm, Ulm, Germany PubMed articles Google scholar articles
Matthis Synofzik Department of Neurodegenerative Diseases and Center of Neurology, Hertie Institute for Clinical Brain Research, Tübingen, GermanyGerman Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany PubMed articles Google scholar articles
Raquel Sanchez-Valle Alzheimer’s Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d’Investigacións Biomèdiques August Pi I Sunyer, Barcelona, SpainAlzheimer’s disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d’Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain PubMed articles Google scholar articles
Rik Vandenberghe Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Flanders, BelgiumNeurology Service, KU Leuven University Hospitals Leuven, Leuven, Flanders, Belgium PubMed articles Google scholar articles
Robert Jr Laforce Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques du CHU de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Roberta Ghidoni Molecular Markers Lab, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy PubMed articles Google scholar articles
Sandro Sorbi Department of Neuroscience, Psychology, Drug Research, and Child Health, University of Florence, Florence, Italy PubMed articles Google scholar articles
Simon Ducharme McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, Montreal, Quebec, CanadaDepartment of Psychiatry, McGill University Health Centre, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Mario Masellis Neurology, Sunnybrook Health Sciences Centre, Toronto, Ontario, CanadaMedicine, Neurology, University of Toronto, Toronto, Ontario, Canada PubMed articles Google scholar articles
Jonathan D Rohrer Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK PubMed articles Google scholar articles
Elizabeth Finger Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada PubMed articles Google scholar articles
on behalf of the Genetic FTD Initiative, GENFI
Google scholar articles

Correspondence to Dr Elizabeth Finger, Clinical Neurological Sciences, University of Western Ontario, London, ON N6A 3K7, Canada; elizabeth.finger{at}lhsc.on.ca

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Citation

Tavares TP, Mitchell DGV, Coleman KK on behalf of the Genetic FTD Initiative, GENFI, et al

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration

Journal of Neurology, Neurosurgery & Psychiatry 2020;91:975-984.

Publication history

Received February 7, 2020
Revised April 14, 2020
Accepted April 20, 2020
First published August 7, 2020.

Online issue publication

August 14, 2020

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