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Original research
Real-life survey of pitfalls and successes of precision medicine in genetic epilepsies

Authors

  • Simona Balestrini Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, and Chalfont Centre for Epilepsy, Gerrard Cross, UK Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy PubMed articlesGoogle scholar articles
  • Daniela Chiarello Institute of Child Health, University College of London (UCL) Great Ormond Street NIHR BRC, London, UK Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Maria Gogou Institute of Child Health, University College of London (UCL) Great Ormond Street NIHR BRC, London, UK Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Katri Silvennoinen Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, and Chalfont Centre for Epilepsy, Gerrard Cross, UK PubMed articlesGoogle scholar articles
  • Clinda Puvirajasinghe Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Wendy D Jones Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, and Chalfont Centre for Epilepsy, Gerrard Cross, UK Institute of Child Health, University College of London (UCL) Great Ormond Street NIHR BRC, London, UK Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Philipp Reif Epilepsy Center Frankfurt Rhine-Main University of Frankfurt, University of Frankfurt, Frankfurt Rhine Main, Germany Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER) Goethe-University Frankfurt, Frankfurt am Main, Germany Epilepsy Center Hessen and Department of Neurology, Philipps-University, Marburg, Germany PubMed articlesGoogle scholar articles
  • Karl Martin Klein Epilepsy Center Frankfurt Rhine-Main University of Frankfurt, University of Frankfurt, Frankfurt Rhine Main, Germany Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER) Goethe-University Frankfurt, Frankfurt am Main, Germany Epilepsy Center Hessen and Department of Neurology, Philipps-University, Marburg, Germany Departments of Clinical Neurosciences, Medical Genetics and Community Health Sciences, Hotchkiss Brain Institute & Alberta Children’s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada PubMed articlesGoogle scholar articles
  • Felix Rosenow Epilepsy Center Frankfurt Rhine-Main University of Frankfurt, University of Frankfurt, Frankfurt Rhine Main, Germany Department of Neurology, University Hospital Frankfurt and LOEWE Center for Personalized Translational Epilepsy Research (CePTER) Goethe-University Frankfurt, Frankfurt am Main, Germany Epilepsy Center Hessen and Department of Neurology, Philipps-University, Marburg, Germany PubMed articlesGoogle scholar articles
  • Yvonne G Weber Department of Neurology and Epileptology, University of Tübingen, Tubingen, Germany Department of Epileptology and Neurology, University of Aachen, Aachen, Germany PubMed articlesGoogle scholar articles
  • Holger Lerche Epilepsy Center Frankfurt Rhine-Main University of Frankfurt, University of Frankfurt, Frankfurt Rhine Main, Germany Department of Neurology and Epileptology, University of Tübingen, Tubingen, Germany PubMed articlesGoogle scholar articles
  • Susanne Schubert-Bast Epilepsy Center Frankfurt Rhine-Main University of Frankfurt, University of Frankfurt, Frankfurt Rhine Main, Germany PubMed articlesGoogle scholar articles
  • Ingo Borggraefe Department of Pediatric Neurology, Dr von Haunerschen Kinderspital, University of Munich, Munich, Germany PubMed articlesGoogle scholar articles
  • Antonietta Coppola Department of Neuroscience, Reproductive and Odontostomatological Sciences, Epilepsy Centre, Federico II University, Naples, Italy PubMed articlesGoogle scholar articles
  • Serena Troisi Department of Neuroscience, Reproductive and Odontostomatological Sciences, Epilepsy Centre, Federico II University, Naples, Italy PubMed articlesGoogle scholar articles
  • Rikke S Møller The Danish Epilepsy Centre Filadelfia, Dianalund, and Institute for Regional Health Services Research, University of Southern Denmark, Odense, Denmark PubMed articlesGoogle scholar articles
  • Antonella Riva Department of Neurosciences, Rehabilitation, Ophtalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy PubMed articlesGoogle scholar articles
  • Pasquale Striano Department of Neurosciences, Rehabilitation, Ophtalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy IRCCS ‘G. Gaslini’ Institute, Genova, Italy PubMed articlesGoogle scholar articles
  • Federico Zara Department of Neurosciences, Rehabilitation, Ophtalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy IRCCS ‘G. Gaslini’ Institute, Genova, Italy PubMed articlesGoogle scholar articles
  • Cheryl Hemingway Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Carla Marini Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy Child Neurology and Psychiatric Unit, Salesi Children's Hospital, Ancona, Italy PubMed articlesGoogle scholar articles
  • Anna Rosati Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy PubMed articlesGoogle scholar articles
  • Davide Mei Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy PubMed articlesGoogle scholar articles
  • Martino Montomoli Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy PubMed articlesGoogle scholar articles
  • Renzo Guerrini Neurology Unit and Neurogenetics Laboratories, Meyer Children Hospital, Florence, Italy PubMed articlesGoogle scholar articles
  • J Helen Cross Institute of Child Health, University College of London (UCL) Great Ormond Street NIHR BRC, London, UK Great Ormond Street Hospital for Children, London, UK PubMed articlesGoogle scholar articles
  • Sanjay M Sisodiya Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, and Chalfont Centre for Epilepsy, Gerrard Cross, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Sanjay M Sisodiya, Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, London, UK; s.sisodiya{at}ucl.ac.uk
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Citation

Balestrini S, Chiarello D, Gogou M, et al
Real-life survey of pitfalls and successes of precision medicine in genetic epilepsies

Publication history

  • Received December 19, 2020
  • Revised February 20, 2021
  • Accepted March 28, 2021
  • First published April 26, 2021.
Online issue publication 
May 24, 2022

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