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  • Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances

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Neurodegeneration
Review
Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances
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Authors

  • Joyce R. Chong Memory, Aging and Cognition Centre, National University Health Systems, Singapore Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore PubMed articlesGoogle scholar articles
  • Nicholas J. Ashton Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden Psychology and Neuroscience, King's College London, Institute of Psychiatry, Maurice Wohl Institute Clinical Neuroscience Institute, London, UK NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia, South London and Maudsley NHS Foundation, London, UK Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden PubMed articlesGoogle scholar articles
  • Thomas K. Karikari Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Tomotaka Tanaka Memory, Aging and Cognition Centre, National University Health Systems, Singapore Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan Clinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore PubMed articlesGoogle scholar articles
  • Michael Schöll Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK PubMed articlesGoogle scholar articles
  • Henrik Zetterberg Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden UK Dementia Research Institute at UCL, University College London, London, UK PubMed articlesGoogle scholar articles
  • Kaj Blennow Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden UK Dementia Research Institute at UCL, University College London, London, UK PubMed articlesGoogle scholar articles
  • Christopher P. Chen Memory, Aging and Cognition Centre, National University Health Systems, Singapore Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore PubMed articlesGoogle scholar articles
  • Mitchell K.P. Lai Memory, Aging and Cognition Centre, National University Health Systems, Singapore Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Mitchell K.P. Lai, Department of Pharmacology, National University of Singapore, Unit 09-01, 14 Medical Drive, Kent Ridge 117599, Singapore; Mitchell.lai{at}dementia-research.org
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Citation

Chong JR, Ashton NJ, Karikari TK, et al
Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances
Journal of Neurology, Neurosurgery & Psychiatry 2021;92:1231-1241.

Publication history

  • Received June 13, 2021
  • Accepted August 30, 2021
  • First published September 11, 2021.
Online issue publication 
October 13, 2021

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