Fronto-striatal circuits for cognitive flexibility in far from onset Huntington’s disease: evidence from the Young Adult Study

Christelle Langley; Sarah Gregory; Katie Osborne-Crowley; Claire O'Callaghan; Paul Zeun; Jessica Lowe; Eileanoir B Johnson; Marina Papoutsi; Rachael I Scahill; Geraint Rees; Sarah J Tabrizi; Trevor W Robbins; Barbara Jacquelyn Sahakian

doi:10.1136/jnnp-2020-324104

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Fronto-striatal circuits for cognitive flexibility in far from onset Huntington’s disease: evidence from the Young Adult Study

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Christelle Langley Department of Psychiatry, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Sarah Gregory Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Katie Osborne-Crowley Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK Division of Equity, Diversity and Inclusion, University of New South Wales, Sydney, New South Wales, Australia PubMed articles Google scholar articles
Claire O'Callaghan Department of Psychiatry, University of Cambridge, Cambridge, UK Brain and Mind Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia PubMed articles Google scholar articles
Paul Zeun Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Jessica Lowe Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Eileanoir B Johnson Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Marina Papoutsi Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Rachael I Scahill Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Geraint Rees University College London Institute of Cognitive Neuroscience, UCL, London, UK PubMed articles Google scholar articles
Sarah J Tabrizi Huntington’s Disease Centre, Department of Neurodegenerative disease, Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Trevor W Robbins Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Barbara Jacquelyn Sahakian Department of Psychiatry, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles

Correspondence to Dr Christelle Langley, Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK; cl798{at}medschl.cam.ac.uk

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Langley C, Gregory S, Osborne-Crowley K, et al

Fronto-striatal circuits for cognitive flexibility in far from onset Huntington’s disease: evidence from the Young Adult Study

Journal of Neurology, Neurosurgery & Psychiatry 2021;92:143-149.

Publication history

Received June 5, 2020
Revised August 11, 2020
Accepted September 22, 2020
First published October 31, 2020.

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May 13, 2021

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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