Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

Nick Cunniffe; Khue Anh Vuong; Debbie Ainslie; David Baker; Judy Beveridge; Sorrel Bickley; Patrick Camilleri; Matthew Craner; Denise Fitzgerald; Alerie G de la Fuente; Gavin Giovannoni; Emma Gray; Lorraine Hazlehurst; Raj Kapoor; Ranjit Kaur; David Kozlowski; Brooke Lumicisi; Don Mahad; Björn Neumann; Alan Palmer; Luca Peruzzotti-Jametti; Stefano Pluchino; Jennifer Robertson; Alan Rothaul; Lyndsey Shellard; Kenneth J Smith; Alastair Wilkins; Anna Williams; Alasdair Coles

doi:10.1136/jnnp-2020-324286

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Multiple sclerosis

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Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

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Nick Cunniffe Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Khue Anh Vuong Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Debbie Ainslie Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
David Baker Blizard Institute, Queen Mary University of London, London, UK PubMed articles Google scholar articles
Judy Beveridge Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Sorrel Bickley Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Patrick Camilleri Independent consultant, Stevenage, UK PubMed articles Google scholar articles
Matthew Craner Department of Neurology, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Denise Fitzgerald Wellcome-Wolfson Institute for Experimental Medicine, Queen's Univeristy, Belfast, UK PubMed articles Google scholar articles
Alerie G de la Fuente Wellcome-Wolfson Institute for Experimental Medicine, Queen's Univeristy, Belfast, UK PubMed articles Google scholar articles
Gavin Giovannoni Blizard Institute, Queen Mary University of London, London, UK PubMed articles Google scholar articles
Emma Gray Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Lorraine Hazlehurst Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Raj Kapoor Faculty of Brain Sciences, Queen Square Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Ranjit Kaur Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
David Kozlowski Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Brooke Lumicisi Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Don Mahad Centre for Clinical Brain Sciences, Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Björn Neumann Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Alan Palmer University of Reading, Reading, Berkshire, UK PubMed articles Google scholar articles
Luca Peruzzotti-Jametti Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Stefano Pluchino Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Jennifer Robertson Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Alan Rothaul Independent consultant, Woodstock, Oxfordshire, UK PubMed articles Google scholar articles
Lyndsey Shellard Research Network, Multiple Sclerosis Society, London, UK PubMed articles Google scholar articles
Kenneth J Smith Department of Neuroinflammation, Queen Square Institute of Neurology, University College London, London, UK PubMed articles Google scholar articles
Alastair Wilkins Department of Neurology, University of Bristol, Bristol, UK PubMed articles Google scholar articles
Anna Williams MS Centre, Centre for regenerative medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Alasdair Coles Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles

Correspondence to Dr Nick Cunniffe, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK; ngc26{at}cam.ac.uk

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Cunniffe N, Vuong KA, Ainslie D, et al

Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis

Journal of Neurology, Neurosurgery & Psychiatry 2021;92:295-302.

Publication history

Received June 16, 2020
Revised September 8, 2020
Accepted October 13, 2020
First published November 12, 2020.

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February 12, 2021

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