D01 Two independent validations of a mutant huntingtin protein (MHTT) assay to support the clinical development of mHTT-targeting therapies in HD

David Hawellek; Stephanie Vauleon; Katharina Schutz; Benoit Massonnet; Nanda Gruben; Marianne Manchester; Lauren Boak; Scott Schobel

doi:10.1136/jnnp-2021-EHDN.32

Article info

D: Wet biomarkers

D01 Two independent validations of a mutant huntingtin protein (MHTT) assay to support the clinical development of mHTT-targeting therapies in HD

Authors

David Hawellek Biomarker and Translational Technology Group, Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Stephanie Vauleon Bioanalytical RandD, Regulated Bioanalysis, Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Katharina Schutz Bioanalytical RandD, Regulated Bioanalysis, Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Benoit Massonnet Bioanalytical RandD, Regulated Bioanalysis, Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Nanda Gruben PRA Health Sciences, Early Development Services, Bioanalytical Laboratory, Assen, the Netherlands PubMed articles Google scholar articles
Marianne Manchester Biomarker and Translational Technology Group, Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Lauren Boak F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Scott Schobel F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles

Citation

Hawellek D, Vauleon S, Schutz K, et al

D01 Two independent validations of a mutant huntingtin protein (MHTT) assay to support the clinical development of mHTT-targeting therapies in HD

Journal of Neurology, Neurosurgery & Psychiatry 2021;92:A13.

Publication history

First published September 5, 2021.

Online issue publication

September 05, 2021

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Main menu

Authors

Citation

Publication history

Request permissions

Copyright information

Log in using your username and password

Main menu

Log in using your username and password

You are here

Authors

Citation

Publication history

Request permissions

Copyright information

Read the full text or download the PDF:

Log in using your username and password