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HMR and RMS contributed equally.
Contributors All authors contributed equally to this work. HMR and RS designed/conceptualised the study, acquired/analysed the data, drafted the manuscript and composed the table. MM acquired data and revised the manuscript for intellectual content. JFG designed/conceptualized the study, analysed the data and revised the manuscript for intellectual content. BMS designed/conceptualised the study, acquired/analysed the data and drafted the manuscript and supervised the study.
Funding This work was supported by the following funders: UK Medical Research Council (MR/P006493/1); National Institute for Health Research, UK (ICA-CDRF-2017-03-070); The Racing Foundation (197/229); Imperial Health Charity (GG1516\100028); U.S. Department of DefenseDefence (CDMRP – FAIN#: W81XWH1810760).
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.