Footnotes

• Contributors ES and CZ have participated in the collection, analysis and interpretation of data.

  AML and CH have participated in the design and execution of the study and in the interpretation of data. Y-YP has participated in the collection, design, execution and interpretation of data.

  A

  A has participated in the analysis and interpretation of data.AEL has participated in the design, analysis and interpretation of data. EM has participated in the design and execution of the study and in the collection, analysis and interpretation of data.

• Funding This study was supported by a CurePSP grant.

• Competing interests EL has received honoraria from Medtronic, Boston Scientific, St Jude, Aleva for consulting and is co-founder of Functional Neuromodulation. CZ has received honoraria or consulting fees from AbbVie, Merz, Teva, Lundbeck, UCB, Acadia and Cynapsus. AEL has served as an advisor for Abbvie, Acorda, Avanir Pharmaceuticals, Bristol Myers Squibb, Cipla, Intekrin and Merck; received honoraria from Medichem, Medtronic, Teva, UCB, AbbVie; received grants from Brain Canada, Canadian Institutes of Health Research, Edmond J Safra Philanthropic Foundation, Michael J. Fox Foundation, the Ontario Brain Institute, National Parkinson Foundation, Parkinson Society Canada, Physicians Services Incorporated, W. Garfield Weston Foundation; received publishing royalties from Saunders, Wiley-Blackwell, Johns Hopkins Press and Cambridge University Press; and has served as an expert witness in cases related to the welding industry. EM has received honoraria from Medtronic for consulting services and lecturing and research grant support from Merz and AGIR.

• Patient consent Obtained.

• Ethics approval Toronto Rehab Research Ethics Boards.

• Provenance and peer review Not commissioned; externally peer reviewed.