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The evidence on the association between allergies and multiple sclerosis (MS) disease activity is scarce. In this issue of JNNP, Fakih and colleagues report that patients with MS and food allergies have a higher disease activity compared with patients with no known allergies.
Both genetic and lifestyle/environmental factors are known to contribute to the development and the severity of MS.1 Previously, a series of studies addressed the relationship between food allergies and MS risk with conflicting results.2
In their JNNP article, Fakih et al3 show that patients with MS and self-reported food allergies have more relapses and a higher likelihood of gadolinium-enhancing lesions compared with patients with no known allergies. Using a well-validated cohort from a single centre, 1349 patients with MS were asked about environmental, food and drug allergies. …
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Commissioned; internally peer reviewed.