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Letter
Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2

https://doi.org/10.1136/jnnp-2018-319713

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    Footnotes

    • Contributors SA: western blots on PS and PBMS, data evaluation, writing the manuscript. GE: collaborator and principal investigator. DAH: IHC analysis of PS tissues. AS: statistics. CH: PenCTU Trial Coordinator. COH: chief investigator, design of the trial, data evaluation, cowriting the manuscript.

    • Funding The Brain Tumour Charity, Saddlers House, 100 Reading Road, Yateley, Hampshire, GU46 7RX, UK. DGE is supported by the all Manchester NIHR Biomedical Research Centre (IS-BRC-1215-20007).

    • Competing interests None declared.

    • Patient consent for publication Not required.

    • Provenance and peer review Not commissioned; externally peer reviewed.