Statistics from Altmetric.com
Metabolomics provide a further guide to the development of precision therapies in ALS
A key facet for the establishment of tailored intervention strategies directed against disease relates to the identification of patient subgroups and phenotypes which may then be utilised to predict individual treatment response and suggest future care approaches. Comprehensive clinical phenotyping is essential to reach an early and accurate diagnosis, and for mapping subsequent patterns of progression.1 It further serves to identify correlation between the variables of clinical presentation and disease burden, potentially enabling biomarker development.2 In turn, comprehensive patient phenotyping may assist in the stratification necessary to identify which patients may benefit most from a specific intervention.3 With these concepts in mind, the study by Goutman and colleagues delineates a role for advanced metabolomic analyses to gain insight into …
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Commissioned; internally peer reviewed.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.