Footnotes

• CS and YW are joint first authors.

• CS and YW contributed equally.

• Contributors CS and YW drafted the manuscript. CS, CL, XF and SY acquired the clinical data. YW, ZL and QK acquired the MRI data. CS, YW, ZYX and ZHX analysed the data. ZZ, BW, YZ and JA provided MRI technical support. YY, ZW and WZ designed and conceptualized study. YY and ZZ revised the manuscript.

• Funding This work was supported by the National Natural Science Foundation of China (81961128030 and 82001804), the Natural Science Foundation of Beijing Municipality (7191003), the Ministry of Science and Technology of China grant (2016YFC1300605 and 2019YFA0707103), the Capital’s Funds for Health Improvement and Research (CFH2020-2-5115), and the Strategic Priority Research Program of Chinese Academy of Science (XDB32010300).

• Competing interests QK and JA were employed by Siemens and did technique support for the study.

• Provenance and peer review Not commissioned; externally peer reviewed.

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