Footnotes

• DZ, AL, XL and WZ contributed equally.

• Contributors DZ and TY designed the study; DZ, AL, XL, WZ, YL, C-YZ and HZ performed the experiments; DZ, AL, XL, WZ and TY analysed the results and wrote the paper. All authors read and approved the final version of the manuscript.

• Funding Supported by grants from the Basic Public Welfare Project of Zhejiang Province (LGF21H090008), Ningbo Natural Science Foundation (2019A610297) to DZ; Natural Science Foundation of Zhejiang Province (LQ21H170001), Zhejiang Medical and Health Science and Technology programme (2020KY285 and 2020KY286) to XL and WZ; Science and Technology Commission of Shanghai Municipality (18JC1420304) to TFY; NSFC (82071372), Guangdong Key Laboratory of Non-human Primate Research (2020B121201006), Outstanding Scholar Program of Bioland Laboratory (2018GZR110102002), Science and Technology Program of Guangzhou (202007030012) to AL.

• Competing interests None declared.

• Provenance and peer review Not commissioned; externally peer reviewed.

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