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Serum peroxiredoxin 3 is reduced in genetic carriers of Parkinson’s disease

http://dx.doi.org/10.1136/jnnp-2022-329433

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    Footnotes

    • ASN and JT are joint first authors.

    • LCT and EKT are joint senior authors.

    • Contributors AN and YT contributed equally to this paper. Conception and design: AN, YT and EKT. Acquisition of data: YT, EN, KYT, WLA, LT and EKT. Analysis and interpretation of data: AN and YT. Writing of the first draft: AN and YT. Review and critique: EKT. Reviewed manuscript: all authors.

    • Funding This study was funded by Singapore’s National Medical Research Council (AN by the Clinician-Scientist New Investigator Grant (CNIG/1165/2017) and Transition Award (MOH-TA18may-0003); EKT and LT by the Parkinson’s disease Translational and Clinical Research flagship grant (TCR12dec010), Open Fund Large Collaborative Grant (MOH-OFLCG18May-0002), and Singapore Translational Research (STaR) Investigator award (NMRC/STaR/014/2013)). Part of the data and biospecimens used in this study were obtained from the MJFF LCC, which is coordinated and funded by the Michael J Fox Foundation for Parkinson’s disease research. For up-to-date information on the LCC study, visit https://www.michaeljfox.org/page.html?lrrk2-cohort-consortium.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.