Genetically determined serum serine level has a novel causal effect on multiple sclerosis risk and predicts disability progression

Xin Lin; Yuanhao Yang; Valery Fuh-Ngwa; Xianyong Yin; Steve Simpson-Yap; Ingrid van der Mei; Simon A Broadley; Anne-Louise Ponsonby; Ausimmune/ AusLong Investigators Group; Kathryn P Burdon; Bruce V Taylor; Yuan Zhou

doi:10.1136/jnnp-2022-330259

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Multiple sclerosis

Original research

Genetically determined serum serine level has a novel causal effect on multiple sclerosis risk and predicts disability progression

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Xin Lin Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles
Yuanhao Yang Mater Research Institute, Translational Research Institute, Woolloongabba, Queensland, Australia Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia PubMed articles Google scholar articles
Valery Fuh-Ngwa Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles
Xianyong Yin Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Steve Simpson-Yap Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia Neuroepidemiology Unit, The University of Melbourne School of Population and Global Health, Melbourne, Victoria, Australia PubMed articles Google scholar articles
Ingrid van der Mei Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles
Simon A Broadley School of Medicine, Griffith University, Gold Coast, Queensland, Australia PubMed articles Google scholar articles
Anne-Louise Ponsonby Murdoch Children's Research Institute, Royal Children's Hospital, University of Melbourne, Parkville, Victoria, Australia Neuroepidemiology Group, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia PubMed articles Google scholar articles
Ausimmune/ AusLong Investigators Group
Google scholar articles
Kathryn P Burdon Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles
Bruce V Taylor Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles
Yuan Zhou Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia PubMed articles Google scholar articles

Correspondence to Dr Yuan Zhou, Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia; Yuan.Zhou{at}utas.edu.au

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Citation

Lin X, Yang Y, Fuh-Ngwa V, et al

Genetically determined serum serine level has a novel causal effect on multiple sclerosis risk and predicts disability progression

Journal of Neurology, Neurosurgery & Psychiatry 2023;94:526-531.

Publication history

Received August 24, 2022
Accepted January 19, 2023
First published February 2, 2023.

Online issue publication

October 18, 2023

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