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Correspondence
Genotype predisposition to leukoaraiosis
  1. Z Szolnoki1,
  2. M Szabó1,
  3. F Somogyvári2
  1. 1Department of Neurology and Neurophysiology, Pándy Kálmán County Hospital, Gyula, Hungary
  2. 2Central Laboratory, Pándy Kálmán County Hospital
  1. Correspondence to:
 Dr Z Szolnoki, H-5600 Békéscaba, Pipacs köz 9, Hungary;
 szolnoki99{at}hotmail.com

https://doi.org/10.1136/jnnp.73.3.352-a

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    Leukoaraiosis, which can cause symptoms ranging from a mild cognitive impairment to severe subcortical dementia,1 is a significant public health problem. One quarter of subjects aged 65 years or over are affected by some degree of white matter changes.2 Ischaemic demyelination and small vessel disease seem to be important features of the underlying pathological process of this entity.1,2 Age, hypertension, and a previous stroke event have been proved to be the main clinical risk factors. …

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