eLetters

154 e-Letters

published between 2008 and 2011

  • Methodological flaws in meta-analysis may lead to misleading conclusions
    Sophie L. Rogers

    Dear Editor,

    We are writing in response to the meta-analysis by Doubal, Hokke and Wardlaw “Retinal Microvascular Abnormalities and Stroke – A Systematic Review” published online on 17 October 2008. While the paper is well written, the topic interesting and potentially important, we have several concerns regarding the methodological rigor of the meta-analysis.

    The fundamental issue is inappropriate poo...

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  • Dementia in parkinson disease: need of clarification
    Gurutz Linazasoro

    Dear Editor,

    I have read with great interest the article by Edison et al about the amyloid load in patients with Parkinson´s disease (PD), PD with dementia (PDD) and dementia with Lewy bodies (DLB) (1). Authors hypothesised that amyloid pathology would be uncommon in PD without dementia, an occasional feature of PDD and present in the majority of DLB cases. This hypothesis was clearly demonstrated (1). However,...

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  • Kernohan Notch, Retractor Crunch, or Interhemispheric Diaschisis:
    Iraj Derakhshan

    Dear Editor,

    I read the article of Yoo et al [1] in the Journal with interest and would like to offer another explanation as to the cause of delayed and weaker response of the right ABP to transcranial magnetic stimulation of the right hemisphere, i.e. interhemispheric diaschisis.

    Firstly, there is substantial number of case reports documenting ipsilateral paralysis in unilateral cranial lesions (e.g....

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  • Various observations on this study
    Tom P Kindlon

    Dear Editor,

    The authors report that "those taking antidepressants had a higher median (interquartile range) body mass ratio (25.0 (21.4-27.6) versus 22.0 (20.0-25.2) (p=0.03) and a shorter median (interquartile range) time on the treadmill (8.6 (6-11) versus 11.0 (8-12) minutes) (p=0.02). They also had a significantly lower mean (SD) peak VO2 (27.9 (9.0) versus 32.8 (7.0) ml/kg/min) (p=0.02)." In the discussion...

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  • STN-DBS in genetic Parkinson's disease patients
    Simon Israeli-Korn

    Dear Editor,

    We have read with interest the article by Soulas and colleagues entitled "Attempted and completed suicides after subthalamic nucleus stimulation for Parkinson's disease". (1)The authors reported a committed suicide rate of at least 1% and a 2% attempted suicide rate in a retrospective cohort of Parkinson's disease (PD) patients who underwent bilateral subthalamic deep brain stimulation (STN DBS). T...

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  • Bowing hand precedes the fingering hand by IHTT
    Masayuki Satoh

    Dear Editor I am pleased to read the comments by Dr. Derakhshan of 27 August, 2008. I would like to reply some questions in following paragraphs.

    First, Dr. Derakhshan wrote that it was hard to understand that the sensory defects of our patient were detected on the right side of the body by the callosal infarction, and this might have been a typographical or clerical error. If you mentioned the somaesthetic...

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  • Cell phone an important emerging tool to diagnose seizures
    Nitin K Sethi

    Dear Editor,

    We read with interest the paper by Leung et al. 1 in which they investigated the agreement between the initial diagnosis/ labels (seizures versus non-specific initial labels like dizziness, syncope and collapse) made at the initial accident and emergency department evaluation and the subsequent final diagnosis (seizure versus non-epileptic event) after inpatient neurological evaluation. As the autho...

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  • Combined central and peripheral relapsing demyelination
    Sabrina Ravaglia

    Dear Editor,

    Zephir et al. (1) report on five patients with a syndrome of combined central and peripheral demyelination, characterized by (i) immunological aetiology, proved by CSF findings, nerve biopsy examination, and response to immune treatments; and (ii) recurrent disease course, with central nervous system (CNS) involvement apparently preceding the onset of peripheral nervous system (PNS) damage by severa...

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  • Bowing hand precedes the fingering hand by IHTT
    Iraj Derakhshan

    Dear Editor,

    I recently read the article by Satoh and colleagues (1) with great interest and have the following question and comments for authors. Their right handed violinist patient became unable to coordinate the movements of bowing and fingering hands as a result of a callosal infarct affecting the entire anterior aspect of the callosum per MRI. From what appears in the figure, as published, the splenium per...

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  • Arteriovenous malformations and pregnancy
    Dennis R Buis

    Dear Editor,

    We read with interest the excellent review by Ng and Kitchen regarding neurosurgery and pregnancy(1). We would like to make two additional remarks. In our opinion the authors failed to address the issue of the pregnant patient with a spinal or dural arteriovenous malformation (sAVM).

    Due to the absence of valves in the epidural venous plexus, the increased intra-abdominal pressure, the additio...

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