92 e-Letters

published between 2013 and 2016

  • Temozolomide for seizure control in low-grade gliomas: role of malignant degeneration
    Wang-Ming Zhang

    We were particularly appreciated the paper by Koekkoek and colleagues1 on temozolomide (TMZ) and seizure frequency after low-grade gliomas (LGG) in a retrospective study. Interestingly, seizure frequency in patients with LGG was remarkably reduced after 6-month TMZ therapy, which was also "an independent prognostic factor for progression-free survival and overall survival",1 indicating associations between seizure reduc...

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  • Serial electrophysiology in Guillain-Barre syndrome: how crucial and of how much clinical relevance?
    Yusuf A Rajabally

    We thank Kokubun et al. [1], for their interest in our study. First, as we stated in our paper [2], our new proposed criteria provided, with a single study, globally, similar proportions and diagnostic shifts, to those found with older criteria and serial studies [3, 4]. There could be no indication from our study that in each and every single individual patient, similar diagnoses would be reached.

    Uncini et a...

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  • Appropriate baseline setting for the evaluation of treatment
    Tomoyuki Kawada

    Troussiere et al. conducted an interesting survey to prevent the progress of Alzheimer's disease in patients with sleep apnoea syndrome (SAS) by continuous positive airway pressure (CPAP) therapy (1). I fundamentally agree with their study outcome. I have a query on the setting of CPAP and non-CPAP groups.

    The cut-off point of 23 for Mini Mental State Examination (MMSE) is widely accepted. The authors mentioned...

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  • CT-negative, lumbar puncture-positive and CTA-negative patients have a low risk of aneurysms.
    Arnab K. Rana

    Dear Editor,

    We are grateful to Bakker et al. for their prospective study in this area.[1]

    Two months prior to this, we published on the topic of CT-negative, lumbar puncture-positive and CT-angiography (CTA) negative patients.[2] Such patients had been reported in 98 published cases. No causative aneurysms were found in neither these nor in the 9 cases which we identified.

    Bakker et al rep...

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  • Screening for post-stroke depression: caution for meta-analysis
    Tomoyuki Kawada

    Meader et al. reported screening abilities of several tools for detecting post-stroke depression by meta-analysis procedures (1). Although the Center of Epidemiological Studies-Depression Scale (CESD), the Hamilton Depression Rating Scale (HDRS) and the Patient Health Questionnaire (PHQ)-9 showed acceptable validity for screening of depression, these tools are not acceptable for clinical use for case- finding. In their a...

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  • Response to research paper of Mr. Wessely
    Andrew Campbell
    This letter was published in error. The text is no longer available.
  • Porphyric neuropathy
    Nobuhiro Yuki

    Reply - We thank Prof Shubhakaran for the interest shown in our article and for highlighting that porphyric neuropathy should be among the differential diagnosis in patients presenting the pharyngeal-cervical- brachial weakness. Indeed, porphyric neuropathy does share some clinical features with Guillain-Barre syndrome and in 50% of cases weakness starts in the upper limbs and therefore may mimic pharyngeal-cervical-brachi...

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  • Re:Levodopa equivalent daily dose and the development of impulse control disorder
    Juan Carlos Martinez Castrillo

    Thank you very much for your interest in our paper and your comments. We have used the levodopa equivalent daily dose (LEDD) of dopamine agonist (ADA) as previously published, and must agree with you as the topic probably needs a thorough review. Anyway, it seems that the occurrence of impulse control disorders (ICDs) in patients with Parkinson's disease (PD) and other diseases in treatment with DA is not just dose-dependen...

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  • Psychiatric side effects of rotigotine mirror its different dopaminergic receptors affinity
    Alfonso Fasano

    Dear Sir,

    We have read with interest the study by Garcia-Ruiz et al.,[1] which investigated the prevalence of Impulse Control Disorders (ICD) in 233 patients with Parkinson's disease (PD) by means of QUIP scale. The authors evaluated for the first time the prevalence of ICD in patients treated with the most commonly prescribed dopamine-agonists (DAs), namely transdermal rotigotine and oral ropinirole and pramipe...

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    Khichar Purnaram Shubhakaran

    I read an interesting article on a variant of Guillain Barré syndrome, by Benjamin and Nobunhiro(March 2014 issue). The review was excellent one but it was lacking one important differential diagnosis among the list of what were mentioned by the eminent authors, that is porphyria1. Porphyric neuropathy is a source of confusion in practice, and patients with porphyria rarely receive the correct diagnosis early in the cour...

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