541 e-Letters

published between 2014 and 2017

  • Cluster headache improved by physical exercise
    Karl E. Ekbom

    Dear Editor,

    I read the case reports of Gotkine et al 1 with great interest and definitely agree with their suggestion that an increase in sympathetic activity may reverse the pain in cluster headache. We saw already in the late 1960´s that spontaneous attacks of cluster headache are not seldom preceded by a shift of the vegetative tone in a parasympathetic direction. Furthermore, the attacks are fairly often associated...

    Show More
  • Anaplastic oligodendroglial tumors: Do gray matter involvement correlate with 1p19q codeletion?
    Gentian Kaloshi

    Gentian Kaloshi, Mentor Petrela

    In their recently published article, Kim et al (1) describe the imaging characteristics of anaplastic oligodendroglioma and anaplastic oligoastrocytoma (AO/AOAs) in an effort to correlate them with molecular alterations. They try to conclude that high-grade oligodendroglial tumors (AO/AOAs) share a similar relationship between radiological characteristics and molecular signatures...

    Show More
  • Disconnection Vs standard anterior temporal lobectomy-which one is better?
    Nitin K. Sethi

    I read with interest the research paper by Massager et al. and the accompanying editorial by Schramm on the long term outcome of surgical disconnection of the epileptic zone in patients with medically refractory nonlesional mesial temporal lobe epilepsy (MTL) 1, 2. High functioning patients with MTL in whom WADA testing reveals bihemispheric dominance for memory frequently experience a decline in either verbal or non-verb...

    Show More
  • Stereotactic modulation of intracerbral energetics
    Richard G Fiddian-Green

    Dear Editor

    The sterotactic neurosurgical techniques being used to treat pain, movement disorders, and [according to The Sunday Times profile on Professor Aziz this week] potentially depression include radiosurgical ablation, deep brain stimulation and microinjections of pharmacological substances.[1-3]

    Might these and other neurocognitive and neuropsychiatric disorders be more sucessfully treated by u...

    Show More
  • Effect of hydration status on accuracy of neuroimaging
    Sarah Keir

    Dear Editor,

    Schmidt et al have performed an interesting study using longitudinal brain imaging to monitor progress of dementia and potential response to drugs aiming to modify the disease (1). The authors describe that patients were taking a number of concomitant drugs and in the paper document that the study groups were well-balanced for concomitant use of low-dose neuroleptics, antidepressants and sedatives/...

    Show More
  • Brain imaging in patients with chronic daily headache
    Sudhir Kumar

    Dear Editor,

    I read with interest the recent article regarding the role of neuroimaging in patients with chronic daily headache (CDH). Though Howard et al. conclude that patients with CDH could be managed without a brain imaging;[1] I would be hesitant to avoid a brain scan in several such patients.

    Firstly, there are no randomized controlled trials on the usefulness or otherwise of neuroimaging in patien...

    Show More
  • Differences in Circadian Variation of Cerebral Thrombosis and Embolic Brain Infarction by Situation
    Shinichi Omama

    Dear editor

    In response to our article, Spengos et al. suggested that we should evaluate the circadian variation of stroke onset separately for the aetiologically different subtypes of ischaemic stroke. Stroke diagnostic criteria of the registry in our study are based essentially on MONICA manual version 1.1, which classifies cerebral infarction (CIF) into that due to cerebral thrombosis (TMB), embolic brain infarction...

    Show More
  • Disease progression or deterioration?
    G Stern

    Most authorities, from Samuel Johnson's to the current Oxford University Dictionary, define "progression" as a change for the better stemming from the Latin "prograde" to improve continuously and "deterioration" as a change for the worse (Latin "deteriore"). Yet most neurological journals appear to accept "disease progression" (as in secondary progressive multiple sclerosis and progressive supranuclear palsy) to indicat...

    Show More
  • Misdiagnosed case of right paraspinal abscess.
    Shantanu Singh, MD

    We read the article by Mackenzie et al. [1] with great interest. We would like to share our experience of an Asian patient in 20s with paraspinal abscess. The patient is a nonsmoker, nondrinker but had been active IV heroine abuser on weekends for past 5 years. He was referred to emergency services for sudden onset of right flank pain, fever (103? Fahrenheit), chills. The pain was progressive, radiated from right flank...

    Show More
  • Reply to Ludger Tebartz van Elst, Dieter Ebert
    Markus Reuber

    Dear Editor

    We thank Ludger Tebartz van Elst and Dieter Ebert for the close reading [1] of our manuscript.[2]

    We concede that it may have been more precise to state that, as a group, patients with psychogenic nonepileptic seizures (PNES), patients with epilepsy and non-clinical controls have personality profiles, which can be distinguished from one another. We did not measure the positive or negative predic...

    Show More