620 e-Letters

  • Intracardiac thrombi in stroke: common, but how relevant?
    Sumeet Singhal

    Dear Editor,

    The study by Sen et al in last month's JNNP (2004;75:1421-1425) regarding risk factors for intracardiac thrombi post-stroke is interesting, but the results require cautious interpretation. The authors present data on a topic of great relevance to clinical management of stroke patients, namely which patients should be referred for transoesophageal echocardiography (TOE). Their attempt to deriv...

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  • Delays caused by increased testosterone
    James M Howard

    Dear Editor,

    I suggest the developmental delays and intellectual problems, exhibited by children of mothers who take valproate for epilepsy, are caused by increased testosterone.

    Learning disabilities have been connected with increased testosterone levels in children (Physiol Behav. 1993 Mar;53(3):583-6). Adab et al, determined that valproate increased the need for "additional educational nee...

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  • auditory neuropathy in patients with Leber's hereditary optic neuropathy
    Benoît Funalot

    Dear Editor,

    We were very interested by the paper of Ceranic and Luxon [1] which identified a progressive auditory neuropathy in two patients with Leber’s hereditary optic neuropathy (LHON). The authors correctly mentioned that we had reported auditory symptoms (bilateral tinnitus) associated with prolongation of the I-III interpeak latency in a patient with LHON harboring the T14484C mutation [2].

    The p...

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  • Mr
    Louis C Kirby

    Dear Sirs, I would like to obtain some equipment for finger tapping testing of PD patients. I would like the name and contact information of the distributor of your test equipment.


    Louis Kirby, MD

  • SinuShunt
    Marek Czosnyka

    Dear Editor,

    We have read the paper by Eklund et al with great interest. It is essential to learn about the hydrodynamic properties of new designs of hydrocephalus shunts assessed independently on the manufacturer.

    Uncomplicated hydrocephalus is easy to manage, but in patients with a history of multiple shunt revisions, hydrodynamics of CSF drainage through the shunt really matters. The shunt should...

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  • A Somatosensory Evoked Rub Epilepsy Induced by Dressing
    Chin-Wei Huang

    Dear Editor,

    We read with great interest the report by Kanemoto et al of rub epilepsy: a somatosensory evoked reflex epilepsy induced by prolonged cutaneous stimulation [1]. We also observed a female patient who had suffered from reflex epilepsy by rubbing movement during dressing.

    A 20-year-female patient, who met with a mild episode of perinatal hypoxia, had suffered from rubbing movement-induc...

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    Dear Editor,

    This paper from Prof. Goadsby is very useful to put certain things in focus. Migraine or other benign head pains could perpass as nothing, and an investigation could show an organic pathology, like the AV malformation.

    The careful medical history, with special topics related to pain and head pain, is fundamental, and the same must be applied to clinical and neurological examination.


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  • Seizure frequency after battery depletion of the VNS device - a reply to Tarver
    Richard A. Wennberg

    Dear Editor

    I appreciate very much the clarification from WB Tarver that the baseline referred to in the VNS Physician’s Manual paragraph entitled "Rebound after stimulation was stopped" refers not to the period of time leading up to end of service (EOS) but rather to the distant preimplantation baseline. This means that one cannot actually ascertain with certainty the percentage of patients improved after batt...

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  • Subthalamic stimulation: double blind assessments
    Paul Krack

    Dear Editor,

    Ford et al [1] report their experience with subthalamic nucleus deep brain stimulation (STN DBS) in advanced PD. In blinded reviews of videotaped neurological examination, off medication UPDRS III (motor) score improved by 26% (baseline 43.8, on stimulation at 12 months 32.3), which is much less than reported by other groups [2]. The authors believe that their more modest results represent a m...

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  • A review of structural magnetic resonance neuroimaging
    Rainer Scheid

    Dear Editor,

    I read with interest the review of structural magnetic resonance imaging by Symms et al. [1] and we appreciate that our work on the diagnosis of diffuse axonal injury by means of T2*-weighted imaging [2] has been mentioned in this review.

    However, I should like to point out that the results of our study have been quoted inaccurately. As Symms et al. [1] correctly report, we fou...

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