RT Journal Article
SR Electronic
T1 Clinical and pathological findings in an unusual infantile motor neurone disease
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 427
OP 431
DO 10.1136/jnnp.34.4.427
VO 34
IS 4
A1 Kohn, Renata
YR 1971
UL http://jnnp.bmj.com/content/34/4/427.abstract
AB An unusual motor neurone disease with a characteristic denervation atrophy of muscle is described in an infant. The striking change is a vacuolization of the cytoplasm of the affected ganglion cells in many motor nuclei of spinal cord and brain-stem, and in the claustrum. To our knowledge this disease has not yet been described in man and similar pathological changes have been found only in a certain strain of mice (`wobbler').