TY - JOUR T1 - Functional compensation in partially denervated muscles JF - Journal of Neurology, Neurosurgery & Psychiatry JO - J Neurol Neurosurg Psychiatry SP - 453 LP - 460 DO - 10.1136/jnnp.34.4.453 VL - 34 IS - 4 AU - A. J. McComas AU - R. E. P. Sica AU - M. J. Campbell AU - A. R. M. Upton Y1 - 1971/08/01 UR - http://jnnp.bmj.com/content/34/4/453.abstract N2 - In patients with various types of chronic motor denervation, the numbers of surviving motor units have been compared with the twitch tensions developed by the same muscle (extensor digitorum brevis). It was found that functional compensation in partially denervated muscles was often marked; in most patients abnormally small twitches occurred only when fewer than 10% of motor axons remained. The factors responsible for this compensation are considered. The twitch speeds of partially denervated muscles differed markedly, even among patients with the same disorder; there was evidence to suggest that the twitches of some motor units might become slower than those found in normal muscles. ER -