PT - JOURNAL ARTICLE AU - Burke, David AU - Skuse, Nevell F. AU - Lethlean, A. Keith TI - Contractile properties of the abductor digiti minimi muscle in paramyotonia congenita AID - 10.1136/jnnp.37.8.894 DP - 1974 Aug 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 894--899 VI - 37 IP - 8 4099 - http://jnnp.bmj.com/content/37/8/894.short 4100 - http://jnnp.bmj.com/content/37/8/894.full SO - J Neurol Neurosurg Psychiatry1974 Aug 01; 37 AB - In two subjects with paramyotonia congenita the isometric torque generated by the abductor digiti minimi and the surface EMG recorded over ADM decreased during prolonged or repetitive contractions, whether these were voluntarily or electrically induced. Isometric twitch times did not alter significantly during this muscle fatigue. Cooling greatly accelerated the fatiguing process. It is suggested that this local muscle weakness is due to a progressive decrease in excitability of the muscle cell membrane.