RT Journal Article
SR Electronic
T1 Ischaemic brain damage in the gerbil in the absence of 'no-reflow'.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 1197
OP 1205
DO 10.1136/jnnp.38.12.1197
VO 38
IS 12
A1 Levy, D E
A1 Brierley, J B
A1 Plum, F
YR 1975
UL http://jnnp.bmj.com/content/38/12/1197.abstract
AB Approximately 40% of gerbils subjected to one hour of unilateral carotid artery occlusion displayed neurological abnormalities during that time. Most such animals were subsequently found to have ischaemic neuronal alterations within the territory of the ipsilateral middle cerebral artery. In contrast, impaired reperfusion ('no-reflow') rarely occurred and cannot therefore be implicated in the pathogenesis of ischaemic brain damage.