PT - JOURNAL ARTICLE AU - I M James AU - A N Hamlyn AU - P C Brant AU - P Hildrew TI - Effect of ornithine alpha oxoglutarate on brain metabolism in patients with chronic liver disease. AID - 10.1136/jnnp.38.3.214 DP - 1975 Mar 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 214--218 VI - 38 IP - 3 4099 - http://jnnp.bmj.com/content/38/3/214.short 4100 - http://jnnp.bmj.com/content/38/3/214.full SO - J Neurol Neurosurg Psychiatry1975 Mar 01; 38 AB - Patients with chronic liver disease, yet without severe encephalopathy, were found to show evidence of increased brain utilization of glucose. The changes were abolished after an intravenous infusion of 15 g ornithine alpha oxoglutarate, given over a period of 15 minutes. The possible implications of these observations are discussed.