PT - JOURNAL ARTICLE AU - S Ahmad AU - J Laidlaw AU - G W Houghton AU - A Richens TI - Involuntary movements caused by phenytoin intoxication in epileptic patients. AID - 10.1136/jnnp.38.3.225 DP - 1975 Mar 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 225--231 VI - 38 IP - 3 4099 - http://jnnp.bmj.com/content/38/3/225.short 4100 - http://jnnp.bmj.com/content/38/3/225.full SO - J Neurol Neurosurg Psychiatry1975 Mar 01; 38 AB - The case histories of four patients who developed choreoathetoid movements during intoxication with phenytoin are presented. Drug intoxication was confirmed in each case by measuring the serum phenytoin concentration. Drug interactions were, in part, responsible for the occurrence of intoxication in three of them. Phenytoin intoxication is not always easy to recognize, particularly when nystagmus is minimal or absent, as in these four patients. The estimation of the serum phenytoin concentration is invaluable in this situation.