RT Journal Article SR Electronic T1 Mental change as an early feature of multiple sclerosis JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 1008 OP 1013 DO 10.1136/jnnp.39.10.1008 VO 39 IS 10 A1 A. C. Young A1 J. Saunders A1 J. R. Ponsford YR 1976 UL http://jnnp.bmj.com/content/39/10/1008.abstract AB Five patients with mental change as a prominent and early feature of an illness which appeared to be multiple sclerosis are reported. All the patients had in addition clinical signs of predominant brain stem involvement and the cerebrospinal fluid findings were similar. It is emphasised that mental change may be an early feature of multiple sclerosis even in those patients in whom the onset of the disease is insidious.