PT - JOURNAL ARTICLE AU - J D Spillane AU - H Urich TI - Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy. AID - 10.1136/jnnp.39.2.105 DP - 1976 Feb 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 105--113 VI - 39 IP - 2 4099 - http://jnnp.bmj.com/content/39/2/105.short 4100 - http://jnnp.bmj.com/content/39/2/105.full SO - J Neurol Neurosurg Psychiatry1976 Feb 01; 39 AB - Two cases are reported of progressive trigeminal neutopathy with nasal ulceration. One patient developed signs of spinal cord involvement 15 years after the onset of trigeminal symptoms and died after a total course of 21 years. Necropsy revealed an unusual trigeminospinal system degeneration with deposition of amyloid-like substances in the affected structures. The other patient is alive eight years after the onset of symptoms, the only indication of a lesion outside the trigeminal nerve being a patch of numbness in one leg.