PT  - JOURNAL ARTICLE
AU  - J B Brierley
AU  - A W Brown
AU  - J Calverley
TI  - Cyanide intoxication in the rat: physiological and neuropathological aspects.
AID  - 10.1136/jnnp.39.2.129
DP  - 1976 Feb 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 129--140
VI  - 39
IP  - 2
4099  - http://jnnp.bmj.com/content/39/2/129.short
4100  - http://jnnp.bmj.com/content/39/2/129.full
SO  - J Neurol Neurosurg Psychiatry1976 Feb 01; 39
AB  - Sodium cyanide was given to rats by intravenous infusion at a rate that would avert apnoea (the first sign of overdosage) in the majority. There was full physiological monitoring in a group under anaesthesia and more limited monitoring in an unanaesthetized group. White matter was damaged in six animals and grey matter additionally in only one. It was concluded that cyanide can damage neurones only through the medium of secondary effects on circulation and respiration.