RT Journal Article
SR Electronic
T1 Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 595
OP 599
DO 10.1136/jnnp.40.6.595
VO 40
IS 6
A1 Nakai, K
A1 Welch, K M
A1 Meyer, J S
YR 1977
UL http://jnnp.bmj.com/content/40/6/595.abstract
AB Transient cerebral ischaemia, produced by temporary unilateral common carotid artery (CCA) occlusion, was studied in the gerbil by means of chronically implanted hydrogen electrodes. Unilateral CCA occlusion produced behavioural signs of neurological deficit only when regional cerebral blood flow values in the ipsilateral cerebral hemisphere fell below a critical range of 0.20-0.22 ml/gm brain/min. Postischaemic poor perfusion (no-reflow) was an infrequent observation after removal of CCA occlusion.