PT - JOURNAL ARTICLE AU - J Merory AU - G H Du Boulay AU - J Marshall AU - J Morris AU - R W Russell AU - L Symon AU - D J Thomas TI - Effect of tinofedrine (Homburg D8955) on cerebral blood flow in multi-infarct dementia. AID - 10.1136/jnnp.41.10.900 DP - 1978 Oct 01 TA - Journal of Neurology, Neurosurgery & Psychiatry PG - 900--902 VI - 41 IP - 10 4099 - http://jnnp.bmj.com/content/41/10/900.short 4100 - http://jnnp.bmj.com/content/41/10/900.full SO - J Neurol Neurosurg Psychiatry1978 Oct 01; 41 AB - Tinofedrine, a new derivative of l-norephedrine, was examined for cerebral vasodilator activity in man. Ten patients with reduced cerebral blood flow (CBF) and multi-infarct dementia were given the drug intravenously. Cerebral blood flow increased significantly by 28% from a mean of 43.3 to 55.5 ml/100 g/min.