RT Journal Article
SR Electronic
T1 Fibrin degradation products in the cerebrospinal fluid of patients with pneumococcal meningitis.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 843
OP 846
DO 10.1136/jnnp.42.9.843
VO 42
IS 9
A1 P G Cleland
A1 J T Macfarlane
A1 D R Baird
A1 B M Greenwood
YR 1979
UL http://jnnp.bmj.com/content/42/9/843.abstract
AB Raised levels of fibrin degradation products were found in the cerebrospinal fluid of nearly all of 35 patients with pneumococcal meningitis. The mean level was higher in patients who died subsequently than in those who survived. Cerebrospinal fluid from patients with pneumococcal meningitis showed increased fibrinolytic activity as assessed by clot lysis, suggesting local production of fibrin degradation products within the subarachnoid space.