RT Journal Article
SR Electronic
T1 Levels of linoleate and arachidonate in red blood cells of healthy individuals and patients with multiple sclerosis.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 106
OP 110
DO 10.1136/jnnp.43.2.106
VO 43
IS 2
A1 Homa, S T
A1 Belin, J
A1 Smith, A D
A1 Monro, J A
A1 Zilkha, K J
YR 1980
UL http://jnnp.bmj.com/content/43/2/106.abstract
AB The major fatty acids were measured in total lipid extracts of red blood cells from 23 control subjects and 31 patients with multiple sclerosis. In the healthy control subjects an inverse correlation (r = -0.83) was found between the percentages of linoleate and arachidonate. In the patients such an inverse correlation was not found. The results suggest an abnormality in the red blood cells of patients with multiple sclerosis specifically with regard to the regulation of the relative amounts of unsaturated fatty acids, and this has implications for the possible treatment of multiple sclerosis with dietary supplements.