PT  - JOURNAL ARTICLE
AU  - K Ricker
AU  - A Haass
AU  - R Rüdel
AU  - R Böhlen
AU  - H G Mertens
TI  - Successuful treatment of paramyotonia congenita (Eulenburg): muscle stiffness and weakness prevented by tocainide.
AID  - 10.1136/jnnp.43.3.268
DP  - 1980 Mar 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 268--271
VI  - 43
IP  - 3
4099  - http://jnnp.bmj.com/content/43/3/268.short
4100  - http://jnnp.bmj.com/content/43/3/268.full
SO  - J Neurol Neurosurg Psychiatry1980 Mar 01; 43
AB  - Recent studies have shown that the sodium conductance of the sarcolemma is disturbed in paramyotonia. Tocainide is a new antiarrhythmic agent which seems to reduce effectively sodium conductance. Eight patients with paramyotonia were treated with tocainide, whereby the paramyotonic stiffness and weakness brought about by cooling could be prevented.