RT Journal Article
SR Electronic
T1 A reassessment of sensory evoked potential parameters in multiple sclerosis: a discriminant analysis approach.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 133
OP 139
DO 10.1136/jnnp.44.2.133
VO 44
IS 2
A1 G Abbruzzese
A1 L Cocito
A1 S Ratto
A1 M Abbruzzese
A1 M Leandri
A1 E Favale
YR 1981
UL http://jnnp.bmj.com/content/44/2/133.abstract
AB The sensitivity of the different parameters (absolute latency, interwave latency, latency asymmetry, amplitude) of both cervical and cerebral responses evoked by stimulation of the median nerve at the wrist was assessed in patients with multiple sclerosis by discriminant analysis. The peak latency of N13 or N20 SEP components or both was found to be more sensitive than their amplitude, provided that a preliminary covariation with the height of the subjects was performed. The measurement of latency asymmetry between the two sides increased the test's sensitivity, while amplitude asymmetry turned out to be of little diagnostic value. A linear discriminant function with four variates (that is mean amplitude, mean latency, latency asymmetry and height of the subject) was computed to summarise the information provided by the different parameters to give a rapid and exact method for the assessment of SEP abnormalities in multiple sclerosis patients.