PT  - JOURNAL ARTICLE
AU  - K Yasuda
AU  - T Alderson
AU  - J Phillips
AU  - K Sikora
TI  - Detection of lymphocytes in malignant gliomas by monoclonal antibodies.
AID  - 10.1136/jnnp.46.8.734
DP  - 1983 Aug 01
TA  - Journal of Neurology, Neurosurgery & Psychiatry
PG  - 734--737
VI  - 46
IP  - 8
4099  - http://jnnp.bmj.com/content/46/8/734.short
4100  - http://jnnp.bmj.com/content/46/8/734.full
SO  - J Neurol Neurosurg Psychiatry1983 Aug 01; 46
AB  - Lymphocytes are not present in normal brain but are known to infiltrate malignant gliomas. The reasons for this infiltration and the signals involved are not understood. The lymphocyte content of 15 malignant gliomas removed at time of surgery was studied, using monoclonal antibodies to T and B cell surface antigens and immunofluorescence. An average of 41% of infiltrating cells possessed surface Ig, with 21% bearing the common T cell marker. There was no evidence of oligoclonal restriction of light chain types.