RT Journal Article
SR Electronic
T1 Myelin basic protein immunoreactivity in serum of neurosurgical patients.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 173
OP 175
DO 10.1136/jnnp.47.2.173
VO 47
IS 2
A1 D G Thomas
A1 N R Hoyle
A1 P Seeldrayers
YR 1984
UL http://jnnp.bmj.com/content/47/2/173.abstract
AB Patients admitted to the neurosurgical wards for the management of nervous system tumours, subarachnoid and intracerebral haemorrhage, head injury, spinal and peripheral nerve lesions, and other miscellaneous neurosurgical conditions, were studied by assay of serum immunoreactivity for myelin basic protein. Of 171 patients, 70% proved to have elevated myelin basic protein activity. In cerebral cases the extent of brain damage assessed by clinical methods appeared to correlate with the appearance of elevated serum myelin basic protein. In spinal and peripheral nerve cases no similar elevation of myelin basic protein was observed.