RT Journal Article SR Electronic T1 The pre-morbid personality of patients with Parkinson's disease. JF Journal of Neurology, Neurosurgery & Psychiatry JO J Neurol Neurosurg Psychiatry FD BMJ Publishing Group Ltd SP 97 OP 100 DO 10.1136/jnnp.48.2.97 VO 48 IS 2 A1 C J Todes A1 A J Lees YR 1985 UL http://jnnp.bmj.com/content/48/2/97.abstract AB A review of the extensive descriptive literature suggests that many Parkinsonian patients exhibit an emotional and attitudinal inflexibility, a lack of affect and a predisposition to depressive illness, which may antecede the development of motor abnormalities by several decades. Introspective, over-controlled, anhedonic personality traits together with suppressed aggresivity are frequently found. It is unclear whether these behavioural patterns are relevant aetiological factors or prodromal symptoms of the disease.