RT Journal Article
SR Electronic
T1 A study of cerebral blood flow and metabolism in epileptic psychosis using positron emission tomography and oxygen.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 201
OP 206
DO 10.1136/jnnp.48.3.201
VO 48
IS 3
A1 B Gallhofer
A1 M R Trimble
A1 R Frackowiak
A1 J Gibbs
A1 T Jones
YR 1985
UL http://jnnp.bmj.com/content/48/3/201.abstract
AB Data are presented on four groups using positron tomography and 15 O inhalation. Compared to age-matched volunteer controls, epileptic patients show regions of low blood flow and hypometabolism as found in previous studies. Epileptic psychotic and non-psychotic patients have been compared, and the main differences noted were lower rOER in the psychotic group, especially in frontal, temporal and basal ganglia regions. When a group of psychotic patients receiving neuroleptic drugs was compared to those free of these medications the rOER was higher in the treated sample, and the rCBF fell, significantly in some areas. These data are discussed in the light of other reports of positron tomography in psychosis.