RT Journal Article
SR Electronic
T1 Magnetic resonance imaging in clinically isolated lesions of the brain stem.
JF Journal of Neurology, Neurosurgery & Psychiatry
JO J Neurol Neurosurg Psychiatry
FD BMJ Publishing Group Ltd
SP 737
OP 743
DO 10.1136/jnnp.49.7.737
VO 49
IS 7
A1 I E Ormerod
A1 A Bronstein
A1 P Rudge
A1 G Johnson
A1 D Macmanus
A1 A M Halliday
A1 H Barratt
A1 E P Du Boulay
A1 B E Kendal
A1 I F Moseley
YR 1986
UL http://jnnp.bmj.com/content/49/7/737.abstract
AB Twenty-seven patients with an isolated brain stem syndrome, thought to be due to demyelination, were examined by magnetic resonance imaging (MRI). A brain stem lesion was identified in 25, and clinically silent lesions outside the brain stem were demonstrated in 20. MRI was more sensitive than evoked potentials in detecting brain stem and other lesions. The scan findings were compared with those in 23 patients with multiple sclerosis, who had chronic brain stem dysfunction, with particular reference to the distribution of abnormalities and the MRI characteristics of the lesions. The relaxation times, T1 and T2, of the lesions were measured by MRI. These values were seen to fall in serial studies of acute lesions, but remained unchanged in the chronic lesions. MRI may therefore allow the age of lesions to be assessed.